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SGLT-2 Antibody

Catalog #: 3690
SKU-Size Size Price Qty
3690-100 100 µg
$310.00
3690-30T 30 µg
$89.00
More Sizes Get Quote

Product Details

Antibody Target SGLT-2
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthetic peptide near the N-terminus of mouse SGLT-2
Accession # Q923I7
Gene ID 246787
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation In phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin
Purification Affinity purified
Species Reactivity Human, mouse, rat
Application Western blot
Application & Usage Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. Other applications have not been determined. The antibody detects 74 kDa SGLT-2 from human, mouse, and rat origins. Reactivity to other species has not
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Sodium glucose co transporters (SGLTs) are located in the brush-border membrane, but transported out of the cell across the basolateral membranes by a facilitated sμgar transporter (GLUT). At least three members of SGLTs (SGLT 1-3) have been cloned and characterized. SGLTs transport a methyl-D-glucoside (a-MDG), a non-metabolized model substrate, in Na-dependent manner. SGLT-1 does not discriminate a-MDG, glucose, and galactose. SGLT2/3 do not transport D-galactose efficiently.


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Maaike Waasdorp, Protease‐activated receptor‐1 contributes to renal injury and interstitial fibrosis during chronic obstructive nephropathy. J Cell Mol Med, Dec 2018;  30485646.
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