An inhibitor of PRMT3
Catalog #: B2846 | abID:

Product Details

Alternate Name 1-isoquinolin-6-yl-3-(2-oxo-2-pyrrolidin-1-ylethyl)urea; N-6-Isoquinolinyl-N'-[2-oxo-2-(1-pyrrolidinyl)ethyl]-urea; N-{2-[(2-Oxo-3-azepanyl)carbamoyl]phenyl}-1-benzothiophene-2-carboxamide
Appearance A crystalline solid
CAS # 1687736-54-4
Molecular Formula C₁₆H₁₈N₄O₂
Molecular Weight 298.34
Purity ≥98%
Solubility ~2 mg/ml in DMSO and DMF
~5 mg/ml in Ethanol
InChi InChI=1S/C16H18N4O2/c21-15(20-7-1-2-8-20)11-18-16(22)19-14-4-3-13-10-17-6-5-12(13)9-14/h3-6,9-10H,1-2,7-8,11H2,(H2,18,19,22)
PubChem CID 90642938
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


SGC707 is a potent, selective and allosteric inhibitor of Protein arginine methyltransferase3 (PRMT3) with an IC₅₀ of 31 nM and KD of 53 nM. It inhibits the methylation of histones in cells at a concentration of 1 µM.

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