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Setd1a polyclonal antibody

Polyclonal Antibody to detect Setd1a in mouse samples.
Catalog #: 6842
$185.00

Product Details

Cat # +Size 6842-50
Size 50 μl
Antibody Target Setd1a
Alternate Name SET1, SET1A, KMT2F
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Polyclonal antibody raised in rabbit against mouse Setd1a (Set domain containing 1A), using three KLH-conjugated synthetic peptides: two containing an amino acid sequence from the N-terminal part of the protein and one containing an amino acid sequence fr
Accession # O15047
Gene ID 9739
Appearance Colorless liquid
Formulation In PBS with 0.05% (W/V) sodium azide.
Purification Whole Anti-Sera
Species Reactivity Mouse.
Application Western blot, ELISA.
Positive Control Western blot: NIH3T3 and embryonic stem cells, ELISA: Peptides.
Application & Usage ELISA: 1:100, Western Blot: 1:500.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

SETD1A is a component of the SET1 histone methyltransferase (HMT) complex. This complex specifically methylates lysine 4 of histone H3, but only if the neighboring lysine 9 residue is not yet methylated. Methylation of H3K4 represents a specific tag for epigenetic transcriptional activation. SETD1A shows a non-overlapping localization with SETD1B, suggesting that both proteins play a specific role in the epigenetic control of chromatin structure and gene expression.


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