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SDF-1beta/CXCL12, feline recombinant

A small cytokine strongly chemotactic for lymphocytes
Catalog #: 4389
SKU-Size Size Price Qty
4389-10 10 μg
$260.00
4389-50 50 μg
$645.00
4389-1000 1 mg
$4,710.00
More Sizes Get Quote

Product Details

Alternate Name C-X-C motif chemokine 12, C-X-C motif chemokine 12, Intercrine reduced in hepatomas, Pre-B cell growth-stimulating factor
Gene Symbol SDF1
Gene ID 493806
Accession # O62657
Source E. coli
Appearance Lyophilized protein
Physical Form Description Sterile filtered and lyophilized with no additives
Molecular Weight 8.5 kDa
Purity by SDS-PAGE ≥97%
Endotoxin Level <0.01 ng/μg
Biological Activity The activity is determined by its ability to chemoattract human T cells at 10 - 75 ng/ml.
Reconstitution Instructions Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at a conce
Amino Acid Sequence KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNKRF KM
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
USAGE For Research Use Only! Not to be used in humans

Details

Stromal Derived Growth Factor-1beta (SDF-1beta), also called CXCL12, is one of two splice variants made by a wide variety of cells when stimulated by inflammatory cytokines such as, TNF, IL-1 or LPS. SDF-1β signals through the G protein-couple receptor, CXCR4, to recruit activated leukocytes. Human SDF-1β shares 100% identity to feline SDF-1β. Recombinant feline SDF-1beta is a non-glycosylated protein, comprised of 72 amino acids, with a molecular weight of 8.5 kDa.


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