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SCF, murine recombinant

based on 2 citations in multiple journalsSCF, murine recombinant24.1 4
A cytokine playing an important role in hematopoiesis, spermatogenesis, & melanogenesis
Catalog #: 4328
SKU-Size Size Price Qty
4328-10 10 μg
$200.00
4328-50 50 μg
$520.00
4328-1000 1 mg
$2,890.00
More Sizes Get Quote

Product Details

Alternate Name Kit ligand Precursor, C-kit ligand, SCF, Mast cell growth factor, MGF, SF, KL-1, Kitl, DKFZp686F2250.
Gene Symbol SCF
Gene ID 17311
Accession # P20826
Source E. coli
Appearance Lyophilized protein
Physical Form Description Lyophilized from 10 mM Sodium Phosphate, pH 6.5
Molecular Weight 18.3 kDa
Purity by SDS-PAGE ≥98%
Purity by ≥98%
Endotoxin Level <0.1 ng/μg
Biological Activity The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is <10 ng/ml, corresponding to a specific activity of >1 x 10⁵ units/mg.
Reconstitution Instructions We recommend a quick spin followed by reconstitution in H₂O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Stem Cell Factor (SCF) is a hematopoietic growth factor that exerts its activity at the early stages of hematopoiesis. SCF stimulates the proliferation of myeloid, erythroid, and lymphoid progenitors in bone marrow cultures. Recombinant murine SCF is an 18.3 kDa protein containing 164 amino acid residues.


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Perry, J. M. et. al. Cooperation between both Wnt/β-catenin and PTEN/PI3K/Akt signaling promotes primitive hematopoietic stem cell self-renewal and expansion. Genes & Dev., Sep 2011; 25: 1928 - 1942.
Fukuda S et al. (2007) Blood 110: 860 - 869.
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