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sCD34, Human Recombinant

Molecular marker for hemopoietic stem cells and progenitors.
Catalog #: P1286

In stock

SKU-Size Size Price Qty
P1286-5 5 µg
$115.00
P1286-20 20 µg
$295.00
More Sizes Get Quote

Product Details

Alternate Name Soluble CD34, Hematopoietic progenitor cell antigen CD34, CD34
Gene Symbol CD34
Accession # P28906
Source CHO cells
Appearance Lyophilized
Molecular Weight 27.4 kDa
Purity by SDS-PAGE ≥ 95%
Endotoxin Level <0.1 EU/μg
Reconstitution Instructions DI water (~1 mg/ml)
Amino Acid Sequence LDNNGTATP ELPTQGTFS NVSTNVSYQ ETTTPSTLG STSLHPVSQ HGNEATTNI TETTVKFTS TSVITSVYG NTNSSVQSQ TSVISTVFT TPANVSTPE TTLKPSLSP GNVSDLSTT STSLATSPT KPYTSSSPI LSDIKAEIK CSGIREVKL TQGICLEQN KTSSCAEFK KDRGEGLAR VLCGEEQAD ADAGAQVCS LLLAQSEVR PQCLLLVLA NRTEISSKL QLMKK
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

CD34 is a highly glycosylated type I membrane protein that is selectively expressed on hematopoietic stem cells and vascular endothelium. It has been widely used as a molecular marker for the identification, isolation, and manipulation of hemopoietic stem cells and progenitors. CD34 can function as a regulator of hemopoietic cell adhesion by mediating the attachment of stem cells to bone marrow stromal cells or other bone marrow components. The full length human CD34 is a 385 amino acid protein, consisting of a 31 amino acid signal sequence, a 74 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain and a 259 amino acid extracellular domain. Recombinant Human sCD34 is a 258 amino acid polypeptide containing only the extracellular domain of the full length CD34 protein.


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