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An Akt activator
Catalog #: 2766
SKU-Size Size Price Qty
2766-1 1 mg
2766-5 5 mg
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Product Details

Alternate Name 2-Amino-6-chloro-α-cyano-3-(ethoxyca­rbonyl)-4H-1-benzopyran-4-acetic acid ethyl ester
Appearance White solid
CAS # 305834-79-1
Molecular Formula C₁₇H₁₇ClN₂O₅
Molecular Weight 364.78
Purity ≥98% by TLC
Solubility DMSO (~ 100 mg/ml) or EtOH (~ 40 mg/ml)
InChi InChI=1S/C17H17ClN2O5/c1-3-23-16(21)11(8-19)13-10-7-9(18)5-6-12(10)25-15(20)14(13)17(22)24-4-2/h5-7,11,13H,3-4,20H2,1-2H3
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


SC-79 is an Akt activator. Binds to the pleckstrin homology (PH) domain of Akt preventing membrane translocation but paradoxically activating it in the cytosol. Enhances Akt phosphorylation by upstream protein kinases. Suppresses excitotoxicity-induced neuronal death in vitro and in vivo.

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