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SBHA

A potent HDAC inhibitor
Catalog #: 2202

In stock

SKU-Size Size Price Qty
2202-50 50 mg
$60.00
2202-250 250 mg
$205.00
More Sizes Get Quote

Product Details

Alternate Name Suberohydroxamic acid; suberic bis-hydroxamic acid; N,N'-dihydroxyoctanediamide
Appearance White to Off-white Solid
CAS # 38937-66-5
Molecular Formula C₈H₁₆N₂O₄
Molecular Weight 204.22
Purity ≥95% by TLC
Solubility H2O (100 mM) or DMSO (100 mM)
SMILES C(CCCC(=O)NO)CCC(=O)NO
InChi InChI=1S/C8H16N2O4/c11-7(9-13)5-3-1-2-4-6-8(12)10-14/h13-14H,1-6H2,(H,9,11)(H,10,12)
InChi Key IDQPVOFTURLJPT-UHFFFAOYSA-N
PubChem CID 5173
MDL Number MFCD00192455
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

SBHA is a competitive histone deacetylase (HDAC) inhibitor that has been shown to inhibit HDAC1 (IC₅₀ = 0.25 μM) and HDAC3 (IC₅₀ = 0.30 μM). SBHA causes cell differentiation, cell cycle arrest, or apoptosis. SBHA also enhances cytotoxicity induced by Oxaliplatin in the colorectal cancer cell lines.


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