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SB 203580

A MAP Kinase inhibitor
Catalog #: 1712
SKU-Size Size Price Qty
1712-1 1 mg
1712-5 5 mg
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Product Details

Alternate Name [4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)1H-imidazole
Appearance White to off-white solid
CAS # 152121-47-6
Molecular Formula C₂₁H₁₆FN₃OS
Molecular Weight 377.43
Purity ≥99% by HPLC
Solubility DMSO (>50 mg/ml) or warm ethanol (12 mg/ml)
InChi InChI=1S/C21H16FN3OS/c1-27(26)18-8-4-16(5-9-18)21-24-19(14-2-6-17(22)7-3-14)20(25-21)15-10-12-23-13-11-15/h2-13H,1H3,(H,24,25)
PubChem CID 176155
MDL Number MFCD00922198
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.


Cell-permeable. Selective inhibitor of p38 mitogen-activated protein kinase (MAP Kinase) (IC₅₀ values are 50 and 500 nM for SAPK2a/p38 and SAPK2b/p38β2 respectively). Displays 100-500-fold selectivity over LCK, GSK3β and PKBα.

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