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Sarecycline

A semi-synthetic tetracycline, narrow-spectrum antibiotic
Catalog #: B3077
SKU-Size Size Price Qty
B3077-5 5 mg
$90.00
B3077-25 25 mg
$360.00
More Sizes Get Quote

Product Details

Alternate Name (4S,4aS,5aR,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-7-[[methoxy(methyl)amino]methyl]-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide; (4S,4aS,5aR,12aS)-4-(dimethylamino)-3,10,12,12a-tetrahydroxy-7-((methoxy(methyl)amino)methyl)-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide; P005672; WC 3035
Appearance Off-white powder
CAS # 1035654-66-0
Molecular Formula C₂₄H₂₉N₃O₈
Molecular Weight 487.51
Purity >95%
Solubility Soluble in DMSO
SMILES CN(C)C1C2CC3CC4=C(C=CC(=C4C(=C3C(=O)C2(C(=C(C1=O)C(=O)N)O)O)O)O)CN(C)OC
InChi InChI=1S/C24H29N3O8/c1-26(2)18-13-8-11-7-12-10(9-27(3)35-4)5-6-14(28)16(12)19(29)15(11)21(31)24(13,34)22(32)17(20(18)30)23(25)33/h5-6,11,13,18,28-29,32,34H,7-9H2,1-4H3,(H2,25,33)/t11-,13-,18-,24-/m0/s1
InChi Key AYUMVPHUMFKFPJ-SBAJWEJLSA-N
PubChem CID 54681908
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Sarecycline is a semi-synthetic tetracycline, narrow-spectrum antibiotic, being developed to treat patients suffering from moderate to severe acne vulgaris. Sarecycline is more active than tetracycline against tet(K) and tet(M) gram-positive bacterial strains, with MICs ranging from 0.125 to 1.0 μl/ml and 8 μl/ml for sarecycline when compared to MICs of 16 to 64 μl/ml and 64 μl/ml for tetracycline respectively.


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