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SAR-260301

A potent and selective Class I phosphatidylinositol-3-kinase-β (PI3K-β) specific inhibitor
Catalog #: B1263
SKU-Size Size Price Qty
B1263-5 5 mg
$145.00
B1263-25 25 mg
$575.00
More Sizes Get Quote

Product Details

Alternate Name (S)-2-(2-(2-methylindolin-1-yl)-2-oxoethyl)-6-morpholinopyrimidin-4(3H)-one
Appearance Crystaline solid
CAS # 1260612-13-2
Molecular Formula C₁₉H₂₂N₄O₃
Molecular Weight 354.4
Purity ≥98% by HPLC
Solubility DMSO
SMILES CC1CC2=CC=CC=C2N1C(=O)CC3=NC(=O)C=C(N3)N4CCOCC4
InChi InChI=1S/C19H22N4O3/c1-13-10-14-4-2-3-5-15(14)23(13)19(25)11-16-20-17(12-18(24)21-16)22-6-8-26-9-7-22/h2-5,12-13H,6-11H2,1H3,(H,20,21,24)/t13-/m0/s1
InChi Key UAXHPOBBKRWJGA-ZDUSSCGKSA-N
PubChem CID 49854424
MDL Number MFCD27987912
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

SAR260301 is a potent and selective Class I phosphatidylinositol-3-kinase-β (PI3K-β) specific inhibitor with an IC₅₀ of 52 nM for this isoform. SAR260301 displays improved physicochemical and in vitro pharmacokinetic properties.


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