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SAR-20347

A novel specific dual inhibitor of JAK1 and tyrosine kinase 2 (TYK2)
Catalog #: B1290
SKU-Size Size Price Qty
B1290-5 5 mg
$125.00
B1290-25 25 mg
$495.00
More Sizes Get Quote

Product Details

Alternate Name 2-(2-Chloro-6-fluorophenyl)-5-[[4-(4-morpholinylcarbonyl)phenyl]amino]-4-oxazolecarboxamide
Appearance Crystalline solid
CAS # 1450881-55-6
Molecular Formula C₂₁H₁₈ClFN₄O₄
Molecular Weight 444.84
Purity ≥98% by HPLC
Solubility DMSO
SMILES C1COCCN1C(=O)C2=CC=C(C=C2)NC3=C(N=C(O3)C4=C(C=CC=C4Cl)F)C(=O)N
InChi InChI=1S/C21H18ClFN4O4/c22-14-2-1-3-15(23)16(14)19-26-17(18(24)28)20(31-19)25-13-6-4-12(5-7-13)21(29)27-8-10-30-11-9-27/h1-7,25H,8-11H2,(H2,24,28)
InChi Key HEDPDFHTQKEORT-UHFFFAOYSA-N
PubChem CID 71727668
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

SAR-20347 is a novel specific dual inhibitor of JAK1 and tyrosine kinase 2 (TYK2), inhibiting JAK1- and/or TYK2-dependent signaling from the IL-12/IL-23, IL-22, and IFN-alpha receptors.


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