A potent Hedgehog (Hh) signaling pathway antagonist
Catalog #: 1976 | abID: ab141481

Product Details

abID ab141481
Alternate Name N-[3-(1H-Benzimidazol-2-yl)-4-chlorophenyl]-3,4,5-triethoxybenzamide
Appearance White to off-white solid
CAS # 329196-48-7
Molecular Formula C₂₆H₂₆ClN₃O₄
Molecular Weight 479.96
Purity ≥95% by NMR
Solubility DMSO (100 mM) or EtOH (100 mM)
InChi InChI=1S/C26H26ClN3O4/c1-4-32-22-13-16(14-23(33-5-2)24(22)34-6-3)26(31)28-17-11-12-19(27)18(15-17)25-29-20-9-7-8-10-21(20)30-25/h7-15H,4-6H2,1-3H3,(H,28,31)(H,29,30)
PubChem CID 1367095
Handling Protect from light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Cell-permeable. A potent antagonist of Hedgehog (Hh) signaling pathway. Antagonizes smoothened receptor activity (KD = 12 nM) and inhibits SAG (Cat. No. 1939-500,1000) activity. SANT-2 should be a useful tool to study the Hh signaling pathway.

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