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Product Details
| Alternate Name | N-[3-(1H-Benzimidazol-2-yl)-4-chlorophenyl]-3,4,5-triethoxybenzamide |
|---|---|
| Appearance | White to off-white solid |
| CAS # | 329196-48-7 |
| Molecular Formula | C₂₆H₂₆ClN₃O₄ |
| Molecular Weight | 479.96 |
| Purity | ≥95% by NMR |
| Solubility | DMSO (100 mM) or EtOH (100 mM) |
| SMILES | CCOC1=CC(=CC(=C1OCC)OCC)C(=O)NC2=CC(=C(C=C2)Cl)C3=NC4=CC=CC=C4N3 |
| InChi | InChI=1S/C26H26ClN3O4/c1-4-32-22-13-16(14-23(33-5-2)24(22)34-6-3)26(31)28-17-11-12-19(27)18(15-17)25-29-20-9-7-8-10-21(20)30-25/h7-15H,4-6H2,1-3H3,(H,28,31)(H,29,30) |
| InChi Key | VQOJFGFKIVFMDH-UHFFFAOYSA-N |
| PubChem CID | 1367095 |
| Handling | Protect from light |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Cell-permeable. A potent antagonist of Hedgehog (Hh) signaling pathway. Antagonizes smoothened receptor activity (KD = 12 nM) and inhibits SAG (Cat. No. 1939-500,1000) activity. SANT-2 should be a useful tool to study the Hh signaling pathway.
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