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Salirasib

A potent Inhibitor of active Ras proteins
Catalog #: B2097

In stock

SKU-Size Size Price Qty
B2097-5 5 mg
$115.00
B2097-25 25 mg
$455.00
More Sizes Get Quote

Product Details

Alternate Name 2-[[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrien-1-yl]thio]benzoic acid; FTS
Appearance White solid
CAS # 162520-00-5
Molecular Formula C₂₂H₃₀O₂S
Molecular Weight 358.54
Purity ≥98% by HPLC
Solubility DMSO (>30 mg/ml)
SMILES CC(=CCCC(=CCCC(=CCSC1=CC=CC=C1C(=O)O)C)C)C
InChi InChI=1S/C22H30O2S/c1-17(2)9-7-10-18(3)11-8-12-19(4)15-16-25-21-14-6-5-13-20(21)22(23)24/h5-6,9,11,13-15H,7-8,10,12,16H2,1-4H3,(H,23,24)/b18-11+,19-15+
InChi Key WUILNKCFCLNXOK-CFBAGHHKSA-N
PubChem CID 5469318
MDL Number MFCD00467723
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Salirasib is a potent Inhibitor of active Ras proteins. It displaces active Ras from the plasma membrane; impairs downstream signaling and inhibits proliferation of endometrial carcinoma cells. Also facilitates Ras degradation. Shown to induce autophagy in several human cancer cell lines.


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