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(S)-Duloxetine hydrochloride

A serotonin and norepinephrine reuptake inhibitor
Catalog #: B2680
SKU-Size Size Price Qty
B2680-50 50 mg
$65.00
B2680-250 250 mg
$195.00
More Sizes Get Quote

Product Details

Alternate Name (S)-N-Methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine hydrochloride, Duloxetine HCl, Cymbalta
Peptide Sequence N/A
Appearance White to off-white solid
CAS # 136434-34-9
Molecular Formula C18H19NOS • HCl
Molecular Weight 333.88
Purity ≥97% by HPLC
Solubility ~ 25 mg/ml DMSO
SMILES CNCCC(C1=CC=CS1)OC2=CC=CC3=CC=CC=C32.Cl
InChi InChI=1S/C18H19NOS.ClH/c1-19-12-11-17(18-10-5-13-21-18)20-16-9-4-7-14-6-2-3-8-15(14)16;/h2-10,13,17,19H,11-12H2,1H3;1H/t17-;/m0./s1
InChi Key BFFSMCNJSOPUAY-LMOVPXPDSA-N
PubChem CID 60834
MDL Number MFCD06407958
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

(S)-Duloxetine hydrochloride belongs to the class of serotonin and norepinephrine reuptake inhibitors. (S)-Duloxetine suppresses spontaneous firing activity in vivo in the dorsal raphe and locus coeruleus (ED50s = 99 and 475 µg/kg, respectively). It is used to treat stress urinary incontinence, psychiatric and metabolic disorders. It is also used for treating diabetic peripheral neuropathic pain, fibromyalgia, chronic musculoskeletal and low back pain (LBP).


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