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S- Adenosylmethionine Antibody (Clone # 118-6)

Monoclonal Antibody to detect S-Adenosylmethionine in samples.
Catalog #: 6940
$285.00

Product Details

Cat # +Size 6940-25
Size 25 µl
Antibody Target S Adenosylmethionine
Alternate Name S- Adenosylmethionine
Host Mouse
Antibody Type Monoclonal
Isotype Mouse IgG2b
Immunogen S-Adenosylmethionine analog Aza-SAM conjugated to KLH
Accession # N/A
Gene ID N/A
Appearance Colorless liquid
Formulation 10 mM PBS (pH 7.4), 0.02% Sodium azide, 50% Glycerol and 1% BSA
Purification Affinity chromatography purified
Species Reactivity All
Application cELISA, FCM, IHC
Positive Control IHC: breast carcinoma tissue, FCM: HepG2 and L02 cell lines
Application & Usage cELISA: 1:10000, FCM: 1:200/400, IHC: 1:200/400.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

S-Adenosylmethionine (SAM) is a naturally occurring compound that is found in almost every tissue and fluid in the body. It is a common co-substrate involved in methyl group transfers. It is made from adenosine triphosphate (ATP) and methionine by methionine adenosyl transferase. Transmethylation, transsulfuration, and aminopropylation are the metabolic pathways that use SAM. Although these anabolic reactions occur throughout the body, most SAM is produced and consumed in the liver. SAM plays a role in the immune system, maintains cell membranes, and helps produce and break down brain chemicals, such as serotonin, melatonin, and dopamine. It works with vitamin B12 and folate (vitamin B9). Being deficient in either vitamin B12 or folate may reduce levels of SAM in your body.


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