Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

S-(5'-Adenosyl)-L-methionine chloride (hydrochloride)

A methyl donor and a cofactor for catechol O-methyltransferase (COMT) and DNA methyltransferase
Catalog #: B2826
SKU-Size Size Price Qty
B2826-5 5 mg
B2826-25 25 mg
More Sizes Get Quote

Product Details

Alternate Name AdoMet SAM, chloride dihydrochloride, S-(5'-Adenosyl)-L-methionine chloride dihydrochloride, (3-Amino-3-carboxypropyl)(((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4, -dihydroxytetrahydrofuran-2-yl)methyl)(methyl)sulfonium chloride dihydrochloride, 5'-[[(3S)-3-amino-3-carboxypropyl]methylsulfonio]-5'-deoxy-adenosine, chloride dihydrochloride, (3-amino-3-carboxypropyl)-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl]-methylsulfanium;chloride;dihydrochloride
Appearance Lyophilized powder
CAS # 86867-01-8
Molecular Formula C₁₅H₂₅Cl₃N₆O₅S
Molecular Weight 507.82
Purity ≥95%
Solubility 1 mg/ml in methanol
5 mg/ml in Water
SMILES C[S+](CCC(C(=O)O)N)CC1C(C(C(O1)N2C=NC3=C2N=CN=C3N)O)O.Cl.Cl.[Cl-]
InChi InChI=1S/C15H22N6O5S.3ClH/c1-27(3-2-7(16)15(24)25)4-8-10(22)11(23)14(26-8)21-6-20-9-12(17)18-5-19-13(9)21;;;/h5-8,10-11,14,22-23H,2-4,16H2,1H3,(H2-,17,18,19,24,25);3*1H/t7?,8-,10-,11-,14-,27?;;;/m1.../s1
PubChem CID 118821583
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -80ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


SAM is a ubiquitous methyl donor. It is a cofactor for methyl transferases such as catechol O-methyltransferase (COMT) and DNA methyltransferase. Most of it is present in the liver, where 85% of all methylation reactions occur. It shows hepatoprotective effects in cultured hepatocytes and mouse models.

Why buy BioVision Products?
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.