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Ruxolitinib phosphate

A potent Janus Kinase (JAK) inhibitor
Catalog #: B2631
SKU-Size Size Price Qty
B2631-5 5 mg
B2631-25 25 mg
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Product Details

Alternate Name INCB-018424 (R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile phosphate INC-424 INCB018424
Appearance White solid
CAS # 1092939-17-7
Molecular Formula C₁₇H₂₁N₆O₄P
Molecular Weight 404.37
Purity ≥98% by HPLC
Solubility >30 mg/ml in DMSO
SMILES N#CC[[email protected]@H](N1N=CC(C2=C3C(NC=C3)=NC=N2)=C1)C4CCCC4.O=P(O)(O)O
InChi InChI=1S/C17H18N6.H3O4P/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16;1-5(2,3)4/h6,8-12,15H,1-5H2,(H,19,20,21);(H3,1,2,3,4)/t15-;/m1./s1
PubChem CID 25127112
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Ruxolitinib phosphate is the phosphate salt form of ruxolitinib, a potent Janus-associated kinase (JAK) inhibitor with potential antineoplastic and immunomodulating activities. Ruxolitinib specifically binds to and inhibits protein tyrosine kinases JAK 1 and 2, which may lead to a reduction in inflammation and an inhibition of cellular proliferation.

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