Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

Ruxolitinib, Free base

A potent JAK inhibitor
Catalog #: 2139
SKU-Size Size Price Qty
2139-5 5 mg
$145.00
2139-25 25 mg
$445.00
More Sizes Get Quote

Product Details

Alternate Name INCB018424; INC18424; NCB018424; NCB18424
Appearance Off-white solid
CAS # 941678-49-5
Molecular Formula C₁₇H₁₈N₆
Molecular Weight 306.37
Purity ≥99% by HPLC
Solubility DMSO (25 mg/ml) or EtOH (~ 15 mg/ml)
SMILES C1CCC(C1)C(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3
InChi InChI=1S/C17H18N6/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16/h6,8-12,15H,1-5H2,(H,19,20,21)/t15-/m1/s1
InChi Key HFNKQEVNSGCOJV-OAHLLOKOSA-N
PubChem CID 25126798
MDL Number MFCD12031592
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Ruxolitinib is a potent and selective Janus kinase (JAK) inhibitor with IC₅₀'s of 2.7 and 4.5 nM for JAK1 and JAK2, respectively. Displays clinically significant activity in myelofibrosis.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.