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Rubella IgM ELISA Kit

A Sandwich ELISA kit for the qualitative detect Rubella IgM in human serum or plasma.
Catalog #: E4667

In stock

$450.00

Product Details

Cat # +Size E4667-100
Size 96 assays
Kit Summary • Detection method- Absorbance (450 nm)
• Species reactivity- Human
• Application- quantitative measurement of Rubella IgM in serum and plasma.
Detection Method Absorbance (450 nm)
Species Reactivity Human
Applications This ELISA kit is used for quantitative measurement of Rubella IgM in serum and plasma.
Features & Benefits • Easy, convenient and time-saving method to measure the level of Rubella IgM in serum and plasma.
• No significant cross-reactivity or interference was observed.
Kit Components • Microplate
• Sample Diluent
• Calibrator
• Positive Control
• Negative Control
• Enzyme conjugate
• TMB Substrate
• Stop Solution
• Wash Buffer (20X)
Storage Conditions 4°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Rubella is usually a mild disease with infrequent complication. In unvaccinated populations, rubella is primarily a childhood disease. Where children are well-immunized, adolescent and adult infections become more evident. Rubella is spread by direct contact with nasal or throat secretions of infected individuals. Symptoms may include a rash, slight fever, joint aches, headache, discomfort, runny nose and reddened eyes. The incubation period for rubella is 12-23 days; in most cases, symptoms appear within 16-18 days. If contracted during the first trimester of pregnancy, Rubella infection can lead to congenital rubella syndrome (CRS). Infection of a pregnant woman may result in a miscarriage, stillbirth or the birth of an infant with abnormalities, which may include deafness, cataracts, heart defects, liver and spleen damage and mental retardation. CRS occurs among at least 25 percent of infants born to women who have had rubella during the first trimester of pregnancy. The presence of IgG antibody to rubella virus is indicative of vaccination or previous exposure. In individuals with acute rubella infection, four-fold or greater increase in IgG antibody level is indicative of recent infection. Rubella IgM antibodies are detected by ELISA in 100% of patients between days 11-25 after onset of the exanthema, in 60-80% of individuals at days 15-25 after vaccination and in 90-97% of infants with congenital rubella between 2 weeks and 3 months after birth. Rubella IgM antibody often persists for 20-30 days after acute infection or vaccination.


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