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RSL3

A glutathione peroxidase 4 (GPX4) inhibitor and an inducer of ferroptosis
Catalog #: B2303
SKU-Size Size Price Qty
B2303-5 5 mg
$195.00
B2303-25 25 mg
$750.00
More Sizes Get Quote

Product Details

Alternate Name (1S,3R)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1-[4-(methoxycarbonyl)phenyl]-1H-pyrido[3,4-b]indole-3-carboxylic acid, methyl ester
Appearance Yellow solid
CAS # 1219810-16-8
Molecular Formula C₂₃H₂₁ClN₂O₅
Molecular Weight 440.88
Purity ≥98% by HPLC
Solubility DMSO (>35 mg/ml)
SMILES COC(=O)C1CC2=C(C(N1C(=O)CCl)C3=CC=C(C=C3)C(=O)OC)NC4=CC=CC=C24
InChi InChI=1S/C23H21ClN2O5/c1-30-22(28)14-9-7-13(8-10-14)21-20-16(15-5-3-4-6-17(15)25-20)11-18(23(29)31-2)26(21)19(27)12-24/h3-10,18,21,25H,11-12H2,1-2H3/t18-,21+/m1/s1
InChi Key TXJZRSRTYPUYRW-NQIIRXRSSA-N
PubChem CID 1750826
MDL Number MFCD30187526
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

RSL3 is a glutathione peroxidase 4 (GPX4) inhibitor and an inducer of ferroptosis. RSL3 increases lipid peroxidase levels in vitro and inhibits tumor formation and progression in vivo.


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