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Rosuvastatin

A HMG-CoA reductase inhibitor
Catalog #: 1955

In stock

SKU-Size Size Price Qty
1955-5 5 mg
$85.00
1955-25 25 mg
$285.00
More Sizes Get Quote

Product Details

Alternate Name (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid
Appearance White to off-white solid
CAS # 287714-41-4
Molecular Formula C₂₂H₂₈FN₃O₆S
Molecular Weight 481.54
Purity ≥98% by HPLC
Solubility DMSO
SMILES CC(C)C1=NC(=NC(=C1C=CC(CC(CC(=O)O)O)O)C2=CC=C(C=C2)F)N(C)S(=O)(=O)C
InChi InChI=1S/C22H28FN3O6S/c1-13(2)20-18(10-9-16(27)11-17(28)12-19(29)30)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)33(4,31)32/h5-10,13,16-17,27-28H,11-12H2,1-4H3,(H,29,30)/b10-9+/t16-,17-/m1/s1
InChi Key BPRHUIZQVSMCRT-VEUZHWNKSA-N
PubChem CID 446157
MDL Number MFCD18783208
Handling Protect from light and air
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Rosuvastatin belongs to a class of compounds called statins that is used to reduce plasma cholesterol levels and prevent cardiovascular disease. It competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase, an enzyme that catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis.


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