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Product Details
| Alternate Name | (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid |
|---|---|
| Appearance | White to off-white solid |
| CAS # | 287714-41-4 |
| Molecular Formula | C₂₂H₂₈FN₃O₆S |
| Molecular Weight | 481.54 |
| Purity | ≥98% by HPLC |
| Solubility | DMSO |
| SMILES | CC(C)C1=NC(=NC(=C1C=CC(CC(CC(=O)O)O)O)C2=CC=C(C=C2)F)N(C)S(=O)(=O)C |
| InChi | InChI=1S/C22H28FN3O6S/c1-13(2)20-18(10-9-16(27)11-17(28)12-19(29)30)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)33(4,31)32/h5-10,13,16-17,27-28H,11-12H2,1-4H3,(H,29,30)/b10-9+/t16-,17-/m1/s1 |
| InChi Key | BPRHUIZQVSMCRT-VEUZHWNKSA-N |
| PubChem CID | 446157 |
| MDL Number | MFCD18783208 |
| Handling | Protect from light and air |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Rosuvastatin belongs to a class of compounds called statins that is used to reduce plasma cholesterol levels and prevent cardiovascular disease. It competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase, an enzyme that catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis.
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