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Product Details
| Alternate Name | (RS)-5-[4-(2-[methyl(pyridin-2-yl)amino]ethoxy)benzyl]thiazolidine-2,4-dione |
|---|---|
| Appearance | White to off-white solid |
| CAS # | 122320-73-4 |
| Molecular Formula | C₁₈H₁₉N₃O₃S |
| Molecular Weight | 357.4 |
| Purity | ≥99% |
| Solubility | DMSO |
| SMILES | CN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC=CC=N3 |
| InChi | InChI=1S/C18H19N3O3S/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15/h2-9,15H,10-12H2,1H3,(H,20,22,23) |
| InChi Key | YASAKCUCGLMORW-UHFFFAOYSA-N |
| PubChem CID | 77999 |
| MDL Number | MFCD00871760 |
| Handling | Protect from light and moisture |
| Storage Conditions | 4°C |
| Shipping Conditions | RT |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Belongs to the thiazolidinedione class of anti-diabetic drugs. A selective ligand of PPARγ and has no PPARα-binding action
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Madhu Asnani-Kishnani, Neonatal Resveratrol and Nicotinamide Riboside Supplementations Sex-Dependently Affect Beige Transcriptional Programming of Preadipocytes in Mouse Adipose Tissue. Front Physiol., Feb 2019; 30800077.
Hyun Park, U. et. al. Additional Sex Comb-like (ASXL) Proteins 1 and 2 Play Opposite Roles in Adipogenesis via Reciprocal Regulation of Peroxisome Proliferator-activated Receptor {gamma}. J. Biol. Chem., Jan 2011; 286: 1354 - 1363.
Bebton C et al. (2008) J. Physiol. 10.113/jphysiol.2007.146563.
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