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Rosiglitazone

based on 2 citations in multiple journalsRosiglitazone24.1 4
A selective ligand of PPARγ
Catalog #: 1559
SKU-Size Size Price Qty
1559-5 5 mg
$60.00
1559-50 50 mg
$195.00
1559-100 100 mg
$295.00
More Sizes Get Quote

Product Details

Alternate Name (RS)-5-[4-(2-[methyl(pyridin-2-yl)amino]ethoxy)benzyl]thiazolidine-2,4-dione
Appearance White to off-white solid
CAS # 122320-73-4
Molecular Formula C₁₈H₁₉N₃O₃S
Molecular Weight 357.4
Purity ≥99%
Solubility DMSO
SMILES CN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC=CC=N3
InChi InChI=1S/C18H19N3O3S/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15/h2-9,15H,10-12H2,1H3,(H,20,22,23)
InChi Key YASAKCUCGLMORW-UHFFFAOYSA-N
PubChem CID 77999
MDL Number MFCD00871760
Handling Protect from light and moisture
Storage Conditions 4°C
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.

Details

Belongs to the thiazolidinedione class of anti-diabetic drugs. A selective ligand of PPARγ and has no PPARα-binding action


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Hyun Park, U. et. al. Additional Sex Comb-like (ASXL) Proteins 1 and 2 Play Opposite Roles in Adipogenesis via Reciprocal Regulation of Peroxisome Proliferator-activated Receptor {gamma}. J. Biol. Chem., Jan 2011; 286: 1354 - 1363.
Bebton C et al. (2008) J. Physiol. 10.113/jphysiol.2007.146563.
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