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Rofecoxib

A non-steroidal anti-inflammatory drug (NSAID) and a potent cyclooxygenase-2 (COX-2) inhibitor
Catalog #: B1982

In stock

SKU-Size Size Price Qty
B1982-10 10 mg
$85.00
B1982-50 50 mg
$325.00
More Sizes Get Quote

Product Details

Alternate Name 4-(4-(methylsulfonyl)phenyl)-3-phenylfuran-2(5H)-one; MK-966; MK966
Appearance Crystalline solid
CAS # 162011-90-7
Molecular Formula C₁₇H₁₄O₄S
Molecular Weight 314.36
Purity ≥98% by HPLC
Solubility DMSO
SMILES CS(=O)(=O)C1=CC=C(C=C1)C2=C(C(=O)OC2)C3=CC=CC=C3
InChi InChI=1S/C17H14O4S/c1-22(19,20)14-9-7-12(8-10-14)15-11-21-17(18)16(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3
InChi Key RZJQGNCSTQAWON-UHFFFAOYSA-N
PubChem CID 5090
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Rofecoxib is a non-steroidal anti-inflammatory drug (NSAID) that acts as a potent cyclooxygenase-2 (COX-2) inhibitor. It displays 1,000-fold selectivity for COX-2 over that of COX-1 (IC₅₀s = 26 nM and > 50 µM in human osteosarcoma cells).


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