Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

ROCK-II Inhibitor

An inhibitor of ROCK-II
Catalog #: B2934
SKU-Size Size Price Qty
B2934-5 5 mg
B2934-25 25 mg
More Sizes Get Quote

Product Details

Alternate Name 3-(4-(1H-pyrazol-4-yl)-2-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-1-(3-methoxybenzyl)-1-methylurea; N-[(3-methoxyphenyl)methyl]-N-methyl-N'-[4-(1H-pyrazol-4-yl)-2-[2-(1-pyrrolidinyl)ethoxy]phenyl]-Urea; 1-[(3-methoxyphenyl)methyl]-1-methyl-3-[4-(1H-pyrazol-4-yl)-2-(2-pyrrolidin-1-ylethoxy)phenyl]urea; 1-(3-Methoxy-benzyl)-1-methyl-3-[4-(1H-pyrazol-4-yl)-2-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-urea
Appearance Solid
CAS # 1225199-26-7
Molecular Formula C₂₅H₃₁N₅O₃
Molecular Weight 449.55
Purity 95%
Solubility Soluble in DMSO
InChi InChI=1S/C25H31N5O3/c1-29(18-19-6-5-7-22(14-19)32-2)25(31)28-23-9-8-20(21-16-26-27-17-21)15-24(23)33-13-12-30-10-3-4-11-30/h5-9,14-17H,3-4,10-13,18H2,1-2H3,(H,26,27)(H,28,31)
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20°C
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.


ROCK Inhibitor-II inhibits the Rho kinase ROCK-II with an IC₅₀ <1 nM. It inhibits the cell based Myosin Light Chain (MLC) bisphosphorylation with an IC₅₀ of 7 nM.

Why buy BioVision Products?
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.