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Ro 61-8048

A high-affinity inhibitor of KMO (kynurenine 3-monoxygenase or kynurenine 3-hydroxylase
Catalog #: 1912
SKU-Size Size Price Qty
1912-5 5 mg
1912-25 25 mg
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Product Details

Alternate Name 3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide
Appearance Off-white solid
CAS # 199666-03-0
Molecular Formula C₁₇H₁₅N₃O₆S₂
Molecular Weight 421.45
Purity ≥98% by HPLC
Solubility DMSO (100 mM) or EtOH (10 mM)
SMILES COC1=C(C=C(C=C1)S(=O)(=O)NC2=NC(=CS2)C3=CC(=CC=C3)[N+](=O)[O-])OC
InChi InChI=1S/C17H15N3O6S2/c1-25-15-7-6-13(9-16(15)26-2)28(23,24)19-17-18-14(10-27-17)11-4-3-5-12(8-11)20(21)22/h3-10H,1-2H3,(H,18,19)
PubChem CID 5282337
MDL Number MFCD11040807
Handling Protect from light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Cell-permeable. A high-affinity small molecule inhibitor of KMO (kynurenine 3-monoxygenase or kynurenine 3-hydroxylase)(Ki = 4.8 nM, IC₅₀ = 37 nM).

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