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RO 20-1724

A potent PDEIV inhibitor
Catalog #: 2042
SKU-Size Size Price Qty
2042-50 50 mg
2042-250 250 mg
More Sizes Get Quote

Product Details

Alternate Name 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone
Appearance White to off-white solid
CAS # 29925-17-5
Molecular Formula C₁₅H₂₂N₂O₃
Molecular Weight 278.35
Purity ≥99% by TLC
Solubility DMSO (~200 mg/ml) or Ethanol (~40 mg/ml)
InChi InChI=1S/C15H22N2O3/c1-3-4-7-20-14-9-11(5-6-13(14)19-2)8-12-10-16-15(18)17-12/h5-6,9,12H,3-4,7-8,10H2,1-2H3,(H2,16,17,18)
PubChem CID 5087
MDL Number MFCD00077397
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Cell-permeable. A potent,selective, cAMP-specific phosphodiesterase inhibitor (PDE IV, IC50 = 2 µM). Inhibits superoxide generation and platelet aggregation stimulated by arachidonic acid. Also inhibits fMLP-induced neutrophil adhesion to vascular endothelial cells.

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