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RKI-1313

A useful negative control for RKI-1447 (Cat.No. 2472)
Catalog #: B1092
SKU-Size Size Price Qty
B1092-5 5 mg
$95.00
B1092-25 25 mg
$375.00
More Sizes Get Quote

Product Details

Alternate Name 1-(3-Methoxybenzyl)-3-[4-(pyridin-4-yl)thiazol-2-yl]urea
Appearance Crystalline solid
CAS # 1342276-76-9
Molecular Formula C₁₇H₁₆N₄O₂S
Molecular Weight 340.4
Purity ≥98% by HPLC
Solubility DMSO
SMILES COC1=CC=CC(=C1)CNC(=O)NC2=NC(=CS2)C3=CC=NC=C3
InChi InChI=1S/C17H16N4O2S/c1-23-14-4-2-3-12(9-14)10-19-16(22)21-17-20-15(11-24-17)13-5-7-18-8-6-13/h2-9,11H,10H2,1H3,(H2,19,20,21,22)
InChi Key BDCUKYUIVYKXCQ-UHFFFAOYSA-N
PubChem CID 53492330
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

RKI-1313 weak inhibitor for ROCK2-dependent signaling and has less effect on phosphorylation levels of ROCK substrates. RKI-1313 serves as a negative control for RKI-1447 (Cat. No. 2472) which is a potent inhibitor of the Rho-associated ROCK kinases with anti-invasive and antitumor activities in breast cancer.


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