Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]


A highly potent ROCK1 and ROCK2 inhibitor
Catalog #: 2472
SKU-Size Size Price Qty
2472-5 5 mg
2472-25 25 mg
More Sizes Get Quote

Product Details

Alternate Name N-[(3-hydroxyphenyl)methyl]-N'-[4-(4-pyridinyl)-2-thiazolyl urea
Appearance Yellow solid
CAS # 1342278-01-6
Molecular Formula C₁₆H₁₄N₄O₂S
Molecular Weight 326.37
Purity ≥98% by HPLC
Solubility DMSO (>50 mg/ml)
InChi InChI=1S/C16H14N4O2S/c21-13-3-1-2-11(8-13)9-18-15(22)20-16-19-14(10-23-16)12-4-6-17-7-5-12/h1-8,10,21H,9H2,(H2,18,19,20,22)
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


A highly potent inhibitor of Rho-associated kinases ROCK1 and ROCK2 (IC₅₀ values: 14.5 nM for ROCK1 and 6.2 nM for ROCK2). RKI-1447 suppresses ROCK-dependent signaling, cell morphology, anchorage-independent cell growth, migration invasion and in vivo growth of mammary tumors.

Why buy BioVision Products?
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.