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Rivastigmine tartrate

An inhibitor of butyrylcholinesterase and acetylcholinesterase
Catalog #: B3093
SKU-Size Size Price Qty
B3093-100 100 mg
$60.00
B3093-500 500 mg
$245.00
More Sizes Get Quote

Product Details

Alternate Name (S)-3-(1-(Dimethylamino)ethyl)phenyl ethyl(methyl)carbamate (2R,3R)-2,3-dihydroxysuccinate; Carbamic acid, ethylmethyl-, 3-((1S)-1-(dimethylamino)ethyl)phenyl ester, (2R,3R)-2,3-dihydroxybutanedioate (1:1); SDZ-ENA 713; ENA 713; Exelon
Appearance White solid
CAS # 129101-54-8
Molecular Formula C₁₈H₂₈N₂O₈
Molecular Weight 400.42
Purity ≥ 95%
Solubility ~16 mg/ml in DMSO and ethanol, ~10 mg/ml in PBS, pH 7.2, ~25 mg/ml in DMF
SMILES CCN(C)C(=O)OC1=CC=CC(=C1)C(C)N(C)C.C(C(C(=O)O)O)(C(=O)O)O
InChi InChI=1S/C14H22N2O2.C4H6O6/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4;5-1(3(7)8)2(6)4(9)10/h7-11H,6H2,1-5H3;1-2,5-6H,(H,7,8)(H,9,10)/t11-;1-,2-/m01/s1
InChi Key GWHQHAUAXRMMOT-MBANBULQSA-N
PubChem CID 6918078
MDL Number MFCD03700731
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.

Details

Rivastigmine is a cholinesterase (ChE) inhibitor that inhibits butyrylcholinesterase (BChE) and acetylcholinesterase (AChE) with IC₅₀ values of 0.037 μM and 4.15 μM respectively. It is used for the treatment of dementia in Alzheimer's disease and Parkinson's disease.


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