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Rilpivirine hydrochloride

A second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI)
Catalog #: B2427

In stock

SKU-Size Size Price Qty
B2427-5 5 mg
B2427-25 25 mg
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Product Details

Alternate Name TMC-278, (E)-4-((4-((4-(2-cyanovinyl)-2,6-dimethylphenyl)amino)pyrimidin-2-yl)amino)benzonitrile hydrochloride, TMC278
Appearance White to off-white solid
CAS # 700361-47-3
Molecular Formula C₂₂H₁₉ClN₆
Purity ≥98% by HPLC
Solubility in DMSO
InChi InChI=1S/C22H18N6.ClH/c1-15-12-18(4-3-10-23)13-16(2)21(15)27-20-9-11-25-22(28-20)26-19-7-5-17 (14-24)6-8-19; /h3-9,11-13H,1-2H3,(H2,25,26,27,28);1H/b4-3+;
PubChem CID 11711114
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Rilpivirine hydrochloride is a diarylpyrimidine derivative that acts as a reverse transcriptase inhibitor with antiviral activity against HIV-1. Rilpivirine is associated with a low rate of transient serum aminotransferase elevations during therapy and has been implicated in rare cases of clinically apparent acute liver injury.

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