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Catalog #: B2737
SKU-Size Size Price Qty
B2737-50 50 mg
B2737-250 250 mg
More Sizes Get Quote

Product Details

Alternate Name NSC-38629; 9,10-dihydro-4,5-dihydroxy-9,10-dioxo-2-anthracenecarboxylic acid
Peptide Sequence N/A
Appearance Yellow solid
CAS # 478-43-3
Molecular Formula C₁₅H₈O₆
Molecular Weight 284.22
Purity ≥95%
Solubility ~10 mg/ml DMSO
SMILES C1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=C(C=C3O)C(=O)O
InChi InChI=1S/C15H8O6/c16-9-3-1-2-7-11(9)14(19)12-8(13(7)18)4-6(15(20)21)5-10(12)17/h1-5,16-17H,(H,20,21)
PubChem CID 10168
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Rhein is an anthraquinone derivative that displays diverse biological activities, including anticancer, antioxidant, and anti-inflammatory activities. Also acts as a Fat mass and obesity-associated protein FTO (mRNA N6-methyladenine demethylase) inhibitor (IC50 = 1.2 - 21 μM; Ki = 1.8 μM). Also inhibits ALKBH3 and ALKBH2 (IC50 values are 5.3 and 9.1 μM, respectively). Sensitizes glioblastoma cells to alkylating agents.

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