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RG 108

A DNA methyltransferase (DNMT) inhibitor
Catalog #: 1679

In stock

SKU-Size Size Price Qty
1679-10 10 mg
$120.00
1679-30 30 mg
$285.00
More Sizes Get Quote

Product Details

Alternate Name N-Phthalyl-L-tryptophan
Appearance Beige to yelllow solid
CAS # 48208-26-0
Molecular Formula C₁₉H₁₄N₂O₄
Molecular Weight 334.33
Purity ≥98% by HPLC
Solubility DMSO (10 mg/ml)
SMILES C1=CC=C2C(=C1)C(=O)N(C2=O)C(CC3=CNC4=CC=CC=C43)C(=O)O
InChi InChI=1S/C19H14N2O4/c22-17-13-6-1-2-7-14(13)18(23)21(17)16(19(24)25)9-11-10-20-15-8-4-3-5-12(11)15/h1-8,10,16,20H,9H2,(H,24,25)/t16-/m0/s1
InChi Key HPTXLHAHLXOAKV-INIZCTEOSA-N
PubChem CID 702558
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

A DNA methyltransferase (DNMT) inhibitor. RG108 causes demethylation and reactivation of tumor suppressor genes, but it does not affect the methylation of centromeric satellite sequences. In combination with BIX 01294 (Cat. No. 1678-5), RG 108 enhances reprogramming.


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