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Retinoic acid

A retinoic acid receptor (RAR) and the retinoid X receptor (RXR) ligand

WARNING: This product can expose you to chemicals including All-trans retinoic acid, which is [are] known to the State of California to cause birth defects or other reproductive harm.  For more information go to
Catalog #: 2218
SKU-Size Size Price Qty
2218-50 50 mg
2218-250 250 mg
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Product Details

Alternate Name ATRA; Tretinoin; NSC 122758; Vitamin A Acid; all-trans Retinoic Acid; NSC 122578
Appearance Yellow solid with an orange tinge
CAS # 302-79-4
Molecular Formula C₂₀H₂₈O₂
Molecular Weight 300.44
Purity ≥98% by titration
Solubility DMSO (20 mg/ml) or Ethanol (0.5 mg/ml)
InChi InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+
PubChem CID 444795
MDL Number MFCD00001551
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Retinoic acid is a metabolite of vitamin A that acts as a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR). RAR and RXR heterodimerize and act as ligand-dependent transcriptional regulators, with roles in development, reproduction, immunity, organogenesis, and cancer. Retinoic acid primes embryonic stem cells to become neurons.

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