Product Details
| Antibody Target | Resistin |
|---|---|
| Alternate Name | Resistin Polyclonal Antibody, Anti-Resistin antibody, Resistin antibody, Anti-Resistin, Resistin, adipose tissue-specific secretory factor, ADSF, adipokine |
| Host | Rabbit |
| Antibody Type | Polyclonal |
| Isotype | Rabbit IgG |
| Immunogen | Recombinant mouse Resistin |
| Accession # | NP_075360 |
| Gene ID | 57264 |
| Appearance | Colorless liquid |
| Concentration | 0.5 mg/ml |
| Formulation | 30 µg (0.5 mg/ml) affinity purified rabbit anti-mouse Resistin polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal. |
| Purification | Affinity purified |
| Species Reactivity | Human, mouse |
| Application | Western blot/IC |
| Application & Usage | Western blot analysis (0.5-4 µg/ml). Based on researcher’s feedback, it can also be used in immunocytochemistry (10-20 µg/ml). However, the optimal conditions should be determined individually. |
| Handling | The antibody solution should be gently mixed before use. |
| Storage Conditions | -20 °C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Resistin (also called adipose tissue-specific secretory factor, ADSF) is a member of the family of adipocyte-secreted proteins. Resistin appears to act on skeletal muscle myocytes, hepatocytes, and adipocytes themselves, where it is sμggested to reduce insulin sensitivity leading to type-2 diabetes.
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Kang, S. et. al. Resistin Promotes Cardiac Hypertrophy via the AMP-activated Protein Kinase/Mammalian Target of Rapamycin (AMPK/mTOR) and c-Jun N-terminal Kinase/Insulin Receptor Substrate 1 (JNK/IRS1) Pathways. J. Biol. Chem., May 2011; 286: 18465 - 18473.
Plaisance EP et al (2009) Am J Physiol Endocrinol Metab.; 296: E549 - E558
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