Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]


based on 1 citations in multiple journalsRepSox14.1 4
A TGF-β type I receptor (ALK5) inhibitor
Catalog #: 1894
SKU-Size Size Price Qty
1894-5 5 mg
1894-25 25 mg
More Sizes Get Quote

Product Details

Alternate Name 2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine; E-616452
Appearance Off-white solid
CAS # 446859-33-2
Molecular Formula C₁₇H₁₃N₅
Molecular Weight 287.32
Purity ≥98% by HPLC
Solubility DMSO (>20 mg/ml)
InChi InChI=1S/C17H13N5/c1-11-4-2-5-16(20-11)17-12(10-19-22-17)13-7-8-14-15(21-13)6-3-9-18-14/h2-10H,1H3,(H,19,22)
PubChem CID 449054
MDL Number MFCD09037561
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Cell-permeable. A TGF-β type I receptor (ALK5) inhibitor. Inhibits ALK5 autophosphorylation (IC₅₀ = 4 nM). Can replace one of the four reprogramming factors Sox-2. RepSox has been successfully used in the direct reprogramming of mouse fibroblasts through induction of Nanog transcription.

Why buy BioVision Products?
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.
Hu et al., Direct Conversion of Normal and Alzheimer's Disease Human Fibroblasts into Neuronal Cells by Small Molecules. Cell Stem Cell Aug 2015, 17:204–212.
For more citations of this product click here