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Renin Inhibitor

A potent renin inhibitor
Catalog #: 2084
SKU-Size Size Price Qty
2084-5 5 mg
2084-25 25 mg
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Product Details

Alternate Name Aliskiren Hemifumarate; (2S,4S,5S,7S)-N-(2-Carbamoyl-2-methylpropyl)-5-amino-4-hydroxy-2,7-diisopropyl-8-[4-methoxy-3-(3-methoxypropoxy)phenyl]-octanamide hemifumarate
Appearance Crystalline solid
CAS # 173334-58-2
Molecular Formula C₃₀H₅₃N₃O₆ • ½C₄H₄O₄
Molecular Weight 609.79
Purity ≥98%
Solubility DMSO (>100 mg/ml) or H2O (>100 mg/ml)
InChi InChI=1S/C30H53N3O6.C4H4O4/c1-19(2)22(14-21-10-11-26(38-8)27(15-21)39-13-9-12-37-7)16-24(31)25(34)17-23(20(3)4)28(35)33-18-30(5,6)29(32)36;5-3(6)1-2-4(7)8/h10-11,15,19-20,22-25,34H,9,12-14,16-18,31H2,1-8H3,(H2,32,36)(H,33,35);1-2H,(H,5,6)(H,7,8)/b;2-1+/t22-,23-,24-,25-;/m0./s1
PubChem CID 9939627
MDL Number MFCD10566724
Handling Protect from moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


A non-peptide, direct renin inhibitor (IC50 = 0.6 nM for human renin) and an anti-hypertensive agent. Aliskiren confers neuronal resistance to Aβ toxicity in primary rat cortical cultures.

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