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Remdesivir

A nucleoside analogue with antiviral activity
Catalog #: B2997
SKU-Size Size Price Qty
B2997-500 500 μg
$195.00
B2997-1000 1 mg
$330.00
More Sizes Get Quote

Product Details

Alternate Name 2-Ethylbutyl (2S)-2-(((S)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo(2,1-f)(1,2,4)triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate; 2-ethylbutyl ((((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate; GS-5734
Appearance White to off-White crystalline powder
CAS # 1809249-37-3
Molecular Formula C₂₇H₃₅N₆O₈P
Molecular Weight 602.58
Purity >99%
Solubility ~125 mg/ml in DMSO
SMILES CCC(CC)COC(=O)C(C)NP(=O)(OCC1C(C(C(O1)(C#N)C2=CC=C3N2N=CN=C3N)O)O)OC4=CC=CC=C4
InChi InChI=1S/C27H35N6O8P/c1-4-18(5-2)13-38-26(36)17(3)32-42(37,41-19-9-7-6-8-10-19)39-14-21-23(34)24(35)27(15-28,40-21)22-12-11-20-25(29)30-16-31-33(20)22/h6-12,16-18,21,23-24,34-35H,4-5,13-14H2,1-3H3,(H,32,37)
InChi Key RWWYLEGWBNMMLJ-YSOARWBDSA-N
PubChem CID 121304016
MDL Number MFCD31657351
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.

Details

Remdesivir is a nucleoside analogue with antiviral activity. It inhibits Middle East respiratory syndrome coronavirus (MERS-CoV)- or severe acute respiratory syndrome coronavirus (SARS-CoV)-infected HAE cultures with EC₅₀ values of 74 nM and 69 nM. It inhibits murine hepatitis virus (MHV) with an EC₅₀ of 30 nM in delayed brain tumor (DBT) cells.


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