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RELMγ, murine recombinant

Promotes or regulates promyelocytic differentiation
Catalog #: 7196
SKU-Size Size Price Qty
7196-10 10 μg
$145.00
7196-50 50 μg
$575.00
More Sizes Get Quote

Product Details

Alternate Name Resistin-like gamma
Gene Symbol Retnlg
Gene ID 10090
Accession # Q7TM98
Source E. Coli
Appearance Lyophilized powder
Physical Form Description Sterile filtered through a 0.2 micron filter. Lyophilized with no additives
Molecular Weight 9.2 kDa
Purity by SDS-PAGE ≥98%
Endotoxin Level < 0.1 ng/μg of protein (<1EU/μg).
Reconstitution Instructions Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carri
Amino Acid Sequence EGTLESIVEK KVKELLANRD DCPSTVTKTF SCTSITASGR LASCPSGMTV TGCACGYGCG SWDIRDGNTC HCQCSTMDWA TARCCQLA
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

RELMγ belongs to a unique family of tissue-specific cytokines termed FIZZ (found in inflammatory zone) and RELM. The other three known members of this family; Resistin, RELMα, and RELMβ, are 85-94 amino acid secreted proteins sharing a conserved C-terminal domain characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. RELMγ is most closely related to RELMα, but is distinctly secreted to bone marrow, spleen, lung, and in peripheral blood granulocytes. The physiological role of RELMγ may include the promotion or regulation of promyelocytic differentiation, although the specific molecular targets of RELMγ have not been identified. Recombinant murine RELMγ is a 9.2 kDa monomeric protein containing 88 amino acid residues.


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