Product Details
| abID | ab269237 |
|---|---|
| Alternate Name | Interleukin-30, IL-30, IL-27/p28, p28, Interleukin-27, Interleukin-27/p28, IL-27, Interleukin-27 subunit α, IL-27 subunit α, IL27-A, Il27, Il27a, IL-27p28. |
| Gene Symbol | IL27 |
| Gene ID | 246779 |
| Accession # | Q8K3I6 |
| Source | E. coli |
| Appearance | Lyophilized protein |
| Molecular Weight | 23.7 kDa |
| Purity by SDS-PAGE | ≥97% |
| Formulation | Lyophilized from a sterile 0.2 µm filtered aqueous solution containing 10 mM sodium bicarbonate, pH 8.5 |
| Endotoxin Level | ≤ 1 EU/µg by LAL method |
| Reconstitution Instructions | Reconstitute in H₂O to a concentration of 0.1-0.5 mg/ml. The solution can then be diluted into other aqueous buffers |
| Handling | Centrifuge the vial prior to opening. |
| Storage Conditions | -20°C |
| USAGE | For Research Use Only! Not to be used in humans |
Details
The p28 subunit of IL-27 (IL-27/p28), also known as Interleukin-30 (IL-30), is a member of the IL-12 family of cytokines. When combined with EBI3 (Epstein-Barr virus induced gene 3), p28 forms a heterodimer known as IL-27. p28 is thought to be a pro-inflammatory cytokine inducing immuno-modulatory effects, but the details of these effects are currently unclear and research is focused on delineating its specific biological functions. Recombinant mouse p28 is a non-glycosylated protein, containing 207 amino acids, with a molecular weight of 23.7 kDa.
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