Product Details
| Alternate Name | Polymeric immunoglobulin receptor, PIGR, PIgR, Poly-Ig receptor, Hepatocellular carcinoma-associated protein TB6, polymeric immunoglobulin receptor precursor MGC125361; MGC125362 FLJ22667 |
|---|---|
| Gene ID | 5284 |
| Accession # | P01833 |
| Source | Baculovirus |
| Appearance | Liquid protein |
| Molecular Weight | 68.9 kDa |
| Purity by SDS-PAGE | ≥ 95% |
| Endotoxin Level | < 1 EU per 1ug of protein (determined by LAL method) |
| Biological Activity | Measured by its binding ability in a functional ELISA with Human IgM. The ED50 range ≤10 ug/ml. |
| Amino Acid Sequence | The target is expressed with the sequence (Lys1-Arg638) of Human p!gR with a His tag at the C-terminus. |
| Handling | Centrifuge the vial prior to opening. |
| Storage Conditions | -20 °C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
The polymeric immunoglobulin receptor is a carrier that transports IgA and IgM across epithelium. The human pIgR has been implicated as a prognostic biomarker for hepatocellular carcinoma progression and metastasis.
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