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Recombinant Coronavirus Nucleoprotein (CoV-NP-NL63)

Plays a role in viral assembly and subgenomic viral RNA transcription and replication
Catalog #: P1507
SKU-Size Size Price Qty
P1507-10 10 μg
$105.00
P1507-50 50 μg
$495.00
More Sizes Get Quote

Product Details

Alternate Name Nucleoprotein, Nucleocapsid protein, NC, N
Accession # Q6Q1R8
Source E. coli
Appearance Sterile Filtered colorless solution
Physical Form Description Liquid
Purity by >95%
Amino Acid Sequence Peptide composed of 130 amino acids.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Human coronavirus NL63 or HCoV-NL63 is a species of coronavirus that was identified in late 2004 in a seven-month-old child with bronchiolitis in the Netherlands. The infecting virus is an enveloped, positive-sense, single-stranded RNA virus that enters its host cell by the ACE2 receptor. Infection with the virus has been confirmed worldwide and has an association with many common symptoms and diseases. Associated diseases include mild to moderate upper respiratory tract infections, severe lower respiratory tract infection, croup and bronchiolitis. The coronavirus genome encodes a spike protein (S), an envelope protein, a membrane protein, and a nucleoprotein in this order. Nucleoprotein packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. It also plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication.


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