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recMAb™ Anti-p53 Antibody

Recombinant rabbit monoclonal antibody to detect p53 expression in human, monkey, dog, hamster and chicken samples. The antibody does not react with mouse and rat samples
Catalog #: A2224
$395.00

Product Details

Cat # +Size A2224-100
Size 100 μg
Antibody Target p53
Alternate Name P53, BCC7, LFS1, BMFS5, TRP53, TP53
Host Rabbit
Antibody Type Monoclonal
Isotype IgG
Immunogen Recombinant full-length human TP53 protein
Accession # P04637
Gene ID 7157
Appearance Colorless liquid
Concentration 1 mg/ml
Formulation In 10 mM PBS
Purification Protein A purified
Species Reactivity Human, Chicken, Does not react with Mouse and Rat, Monkey, Dog, Hamster
Application Immunohistochemistry (IHC), Western Blotting
Application & Usage WB (1-2 µg/ml), IHC (1-2 µg/ml)
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants


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