Product Details
| Cat # +Size | A2242-100 |
|---|---|
| Size | 100 μl |
| Antibody Target | LOXL2 |
| Alternate Name | LOR, LOR2, WS9-14, LOXL2, EC 1.4.3.13, EC 1.4.3 |
| Host | Rabbit |
| Antibody Type | Monoclonal |
| Isotype | IgG |
| Immunogen | Synthetic peptide derived from human LOXL2 |
| Accession # | Q9Y4K0 |
| Gene ID | 4017 |
| Appearance | Colorless liquid |
| Formulation | In PBS, pH 7.4, 150 mM NaCl, 50% glycerol, 0.02% sodium azide |
| Purification | Affinity purified |
| Species Reactivity | Human, Mouse, Rat |
| Application | Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting, Flow Cytometry |
| Application & Usage | WB 1:500-1:5000, IHC 1:50-1:200, IF 1:20-1:200, FC 1:20-1:200 |
| Handling | The antibody solution should be gently mixed before use. |
| Storage Conditions | -20ºC |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyzes the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
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