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RBP4, human recombinant

A specific carrier for retinol in the blood
Catalog #: 4940
SKU-Size Size Price Qty
4940-20 20 μg
$195.00
4940-1000 1 mg
$5,500.00
More Sizes Get Quote

Product Details

Alternate Name Retinol Binding Protein 4, RBP-4, RBP4, Plasma retinol-binding protein, PRBP, RBP.
Gene Symbol RET4
Gene ID 5950
Accession # P02753
Source E. coli
Appearance Liquid
Physical Form Description Sterile filtered solution (1 mg/ml) in PBS, pH 7.4
Molecular Weight 21.0 kDa
Purity by SDS-PAGE ≥95%
Purity by ≥95%
Biological Activity Immune reactive in ELISA using monoclonal anti CD4 in gpl2O capture ELISA assays.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Retinol binding protein 4(RBP4) belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. This protein was found to be expressed and secreted by adipose tissue, and was strongly associated with insulin resistance. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli.RBP4 delivers retinol from the liver to the peripheral tissues. In plasma, the rbp-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli. RBP-4 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 184 amino acids and having a molecular mass of 21 kDa. The Retinol Binding Protein-4 is purified by proprietary chromatographic techniques.


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