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A rapid inducer of apoptosis
Catalog #: 9626
SKU-Size Size Price Qty
9626-10 10 mg
9626-50 50 mg
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Product Details

Alternate Name 9H, 9’H-[9,9’-bifluorene]-9,9’-dicarbaldehyde
Appearance Beige solid
CAS # 1176-09-6
Molecular Formula C₂₈H₁₈O₂
Molecular Weight 386.44
Purity ≥98% by HPLC
Solubility DMSO
InChi InChI=1S/C28H18O2/c29-17-27(23-13-5-1-9-19(23)20-10-2-6-14-24(20)27)28(18-30)25-15-7-3-11-21(25)22-12-4-8-16-26(22)28/h1-18H
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Raptinal is a rapid inducer of apoptosis. Consistent with apoptotic morphological changes, U-937 cells treated with 10 μM Raptinal displays modest (at 30 min) and extensive (at 60 min) blebbing. Consistent with caspase-dependent apoptosis, the pan-caspase inhibitor Q-VD-OPh (Cat. No. 1170) quantitatively blocks the loss in cell viability and cellular blebbing. Raptinal is also found to induce death against various cancer and non-cancerous cell lines with 24 hour IC₅₀ values between 0.7-3.4 μM indicating activity across a wide variety of cell lines.

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