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RANTES Antibody

Catalog #: 5323
$265.00

Product Details

Cat # +Size 5323-100
Size 100 µg
Antibody Target RANTES
Alternate Name Chemokine, CC motif, ligand 5, CCL5, CCL-5, CCL 5
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen E. coli-expressed mature rat RANTES (a.a. 1-70)
Accession # NP_112378
Gene ID 81780
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation 100 µg (0.5 mg/ml) affinity purified rabbit anti-RANTES polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.
Purification Affinity purified
Species Reactivity Mouse, rat
Application Western blot
Application & Usage Western blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually. RAW264.7 cells treated with LPS (15 hr) can be used as a positive control.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

RANTES (regulated upon activation, normal T-cell expressed and secreted) is a 70-amino acid CC chemokine originally cloned from T-cell-specific sequences-enriched cDNA libraries. Both human and murine RANTES are chemotactic for monocytes. Human RANTES is also a chemoattractant for T-cells and eosinophils, as well as an activator of basophils for histamine release. In contrast to other CC chemokines, RANTES is only slowly expressed after activation of leukocytes. It is involved in a number of pathological conditions like chronic inflammation and autoimmune diseases.


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