Product Details
| Cat # +Size | A1002-100 |
|---|---|
| Size | 100 µg |
| Antibody Target | RANTES |
| Alternate Name | C-C motif chemokine 5, EoCP, Eosinophil chemotactic cytokine, SIS-delta, Small-inducible cytokine A5, T cell-specific protein P228, TCP228 |
| Host | Rabbit |
| Antibody Type | Polyclonal |
| Isotype | rabbit IgG |
| Immunogen | human RANTES recombinant protein (Cat. No. 4321) |
| Accession # | P13501 |
| Gene ID | 6352 |
| Appearance | Colorless liquid |
| Concentration | 0.5 mg/ml |
| Formulation | 100 µg (0.5 mg/ml) of antibody in PBS pH 7.2, 0.01 % BSA, 0.03 % ProClin®, and 50 % glycerol. |
| Purification | Affinity purified rabbit IgG |
| Species Reactivity | Human, Mouse |
| Application | Western blot |
| Positive Control | Western blot |
| Application & Usage | Western blot: 1-4 µg/ml |
| Handling | The antibody solution should be gently mixed before use. |
| Storage Conditions | -20 °C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Tissue transglutaminase, a 78-kDa calcium dependent enzyme (EC 2.3.2.13), is found both in the intracellular and the extracellular spaces of various types of tissues. TG2 crosslinks proteins between the ε-amino group of a lysine residue and the γ-carboxamide group of glutamine residue, creating an inter- or intramolecular bond that is highly resistant to proteolysis (protein degradation). TG2 also possesses deamidation, GTP-binding/hydrolyzing, and isopeptidase activities. Intracellular TG2 is thought to play an important role in apoptosis, while extracellular TG2 has been linked to cell adhesion, ECM stabilization, wound healing, receptor signaling, cellular proliferation, and cellular motility.
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