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Ramipril

A potent angiotensin converting-Enzyme (ACE) inhibitor
Catalog #: B2133

In stock

SKU-Size Size Price Qty
B2133-50 50 mg
$75.00
B2133-250 250 mg
$225.00
More Sizes Get Quote

Product Details

Alternate Name (2S,3aS,6aS)-1-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydro-cyclopenta[b]pyrrole-2-carboxylic acid; Altace; HOE498
Appearance White solid
CAS # 87333-19-5
Molecular Formula C₂₃H₃₂N2₂O₅
Molecular Weight 416.51
Purity ≥98% by HPLC
Solubility DMSO (>30 mg/ml)
SMILES CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2C3CCCC3CC2C(=O)O
InChi InChI=1S/C23H32N2O5/c1-3-30-23(29)18(13-12-16-8-5-4-6-9-16)24-15(2)21(26)25-19-11-7-10-17(19)14-20(25)22(27)28/h4-6,8-9,15,17-20,24H,3,7,10-14H2,1-2H3,(H,27,28)/t15-,17-,18-,19-,20-/m0/s1
InChi Key HDACQVRGBOVJII-JBDAPHQKSA-N
PubChem CID 5362129
MDL Number MFCD00865775
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Ramipril is a non-peptide, angiotensin converting enzyme (ACE) inhibitor (IC₅₀ = 5 nM). A prodrug that is hydrolyzed in vivo to the active metabolite ramiprilat. Displays protective effects on endothelium against high-glucose induced dysfunction. Displays antihypertensive effects.


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