Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]


A specific and irreversable inhibitor of HMG-CoA
Catalog #: B1244
SKU-Size Size Price Qty
B1244-500 500 µg
B1244-1000 1 mg
More Sizes Get Quote

Product Details

Alternate Name (2E,4E,7R)-11-[(2R,3R)-3-(Hydroxymethyl)-4-oxooxetan-2-yl]-3,5,7-trimethylundeca-2,4-dienoic acid
Appearance White to off-white solid
CAS # 29066-42-0
Molecular Formula C₁₈H₂₈O₅
Molecular Weight 324.41
Purity ≥95% by HPLC
Solubility DMSO
InChi InChI=1S/C18H28O5/c1-12(8-13(2)9-14(3)10-17(20)21)6-4-5-7-16-15(11-19)18(22)23-16/h9-10,12,15-16,19H,4-8,11H2,1-3H3,(H,20,21)/b13-9+,14-10+/t12-,15-,16-/m1/s1
PubChem CID 6440895
MDL Number MFCD01940046
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


(R,R)-Hymeglusin is a specific and irreversible inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase in vitro and in vivo by covalently modifying the active Cys129 residue of the enzyme. It is a fungal beta-lactone that inhibits mevalonate biosynthesis and is a good target for statins. It displays antimicrobial and anti-fungal activity.

Why buy BioVision Products?
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.